|
|
thioplatensimycin + H2O <=> platensimycin + Sulfide + H+
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21740
|
|
|
|
(7R,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oate + ATP + H+ <=> (7R,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oyl-AMP + diphosphate
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21745
|
|
|
|
sulfur-carrier_protein_with_a_C-terminal_Gly-Gly + ATP + H+ <=> carboxy-adenylated_[sulfur-carrier_protein_with_a_C-terminal_Gly-Gly] + diphosphate
|
2.7.7
|
–
|
| |
MetaCyc:
RXN-21735
|
|
|
|
(11S,16S)-ent-kauran-11,16-epoxy-19-oate + 2-oxoglutarate + O2 <=> (7S,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oate + succinate + CO2
|
1.14.11
|
–
|
| |
MetaCyc:
RXN-21743
|
|
|
|
ent-copalyl_diphosphate + H2O <=> ent-16-alpha-hydroxy-kaurene + diphosphate
|
4.2.3.19
ent-kaurene synthase
|
–
|
| |
BRENDA:
BS416974
MetaCyc:
RXN-21750
|
|
|
|
(3S)-3-hydroxy-homoplatensic-CoA + NAD+ <=> 3-oxo-homoplatensic-CoA + NADH + H+
|
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
|
| |
MetaCyc:
RXN-21760
|
|
|
|
(16R)-ent-kauran-16,19-diol <=> (16R)-hydroxy-ent-kauran-19-oate
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21748
|
|
|
|
2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate <=> H+ + 3-Amino-4-hydroxybenzoic_acid + phosphate + H2O
|
4.1.99.20
3-amino-4-hydroxybenzoate synthase
|
–
|
| |
BRENDA:
BR50715
KEGG:
R10469
MetaCyc:
RXN-13866
SABIO-RK:
12674
|
|
|
|
3-amino-2,4-dihydroxybenzoate + CoA + ATP <=> 3-amino-2,4-dihydroxybenzoyl-CoA + diphosphate + AMP
|
6.2.1
|
–
|
| |
MetaCyc:
RXN-21734
|
|
|
|
ent-16-alpha-hydroxy-kaurene <=> (16R)-ent-kauran-16,19-diol
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21749
|
|
|
|
2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate <=> L-aspartate_4-semialdehyde + dihydroxyacetone_phosphate
|
4.1.2.56
2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase
|
–
|
| |
BRENDA:
BR50999
KEGG:
R10673
MetaCyc:
RXN-13865
SABIO-RK:
12673
|
|
|
|
L-aspartate_4-semialdehyde + phosphate + NADP+ <=> L-4-aspartyl_phosphate + NADPH + H+
|
1.2.1.11
aspartate-semialdehyde dehydrogenase
|
–
|
| |
BRENDA:
BR36772
KEGG:
R02291
MetaCyc:
ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN
SABIO-RK:
2255
|
|
|
|
(7R,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oate + NADP+ <=> (11S,16S)-7-oxo-ent-kauran-11,16-epoxy-19-oate + NADPH + H+
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21741
|
|
|
|
L-aspartate + ATP <=> L-4-aspartyl_phosphate + ADP
|
2.7.2.4
aspartate kinase
|
–
|
| |
BRENDA:
BR47827
KEGG:
R00480
MetaCyc:
ASPARTATEKIN-RXN
SABIO-RK:
912
|
|
|
|
geranylgeranyl_diphosphate <=> ent-copalyl_diphosphate
|
5.5.1.12
copalyl diphosphate synthase
5.5.1.13
ent-copalyl diphosphate synthase
5.5.1.14
syn-copalyl-diphosphate synthase
|
–
–
–
|
| |
BRENDA:
BR40507;
BR44349;
BS386478
KEGG:
R02068;
R06298;
R06312
MetaCyc:
5.5.1.13-RXN;
RXN-4861;
RXN-8528
|
|
|
|
platensicyl-CoA + propionyl-CoA <=> 3-oxo-homoplatensic-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
|
| |
MetaCyc:
RXN-21761
|
|
|
|
(7R,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oyl-CoA + acceptor <=> (4S)-homoplatensicyl-CoA + reduced_acceptor
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21738
|
|
|
|
3-Amino-4-hydroxybenzoic_acid + O2 + NADPH + H+ <=> 3-amino-2,4-dihydroxybenzoate + H2O + NADP+
|
1.14.13.M82
|
–
|
| |
MetaCyc:
RXN-21732
|
|
|
|
(16R)-hydroxy-ent-kauran-19-oate + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> (11S,16S)-ent-kauran-11,16-epoxy-19-oate + H2O + oxidized_ferredoxin
|
1.14.19
|
–
|
| |
MetaCyc:
RXN-21747
|
|
|
|
thiocarboxylated_[sulfur-carrier_protein_with_a_C-terminal_Gly-Gly] + 3-amino-2,4-dihydroxybenzoyl-CoA + H2O <=> 3-amino-2,4-dihydroxybenzoylsulfanide + CoA + sulfur-carrier_protein_with_a_C-terminal_Gly-Gly + H+
|
2.8.1
|
–
|
| |
MetaCyc:
RXN-21737
|
|
|
|
(7S,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oate + NAD+ <=> (11S,16S)-7-oxo-ent-kauran-11,16-epoxy-19-oate + NADH + H+
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21742
|
|
|
|
(4S)-homoplatensicyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> homoplatensic-4-enyl-CoA + reduced_flavodoxin
|
1.3.8
|
–
|
| |
MetaCyc:
RXN-21751
|
|
|
|
sulfurated_[sulfur_carrier] + carboxy-adenylated_[sulfur-carrier_protein_with_a_C-terminal_Gly-Gly] + reduced_acceptor <=> unsulfurated_[sulfur_carrier] + thiocarboxylated_[sulfur-carrier_protein_with_a_C-terminal_Gly-Gly] + AMP + acceptor + H+
|
2.8.1
|
–
|
| |
MetaCyc:
RXN-21736
|
|
|
|
(3S)-3-hydroxy-homoplatensic-CoA <=> homoplatensic-4-enyl-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
|
–
|
| |
MetaCyc:
RXN-21759
|
|
|
|
3-amino-2,4-dihydroxybenzoylsulfanide + platensicyl-CoA + H+ <=> thioplatensimycin + CoA
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21739
|
|
|
|
(7R,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oyl-AMP + CoA <=> (7R,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oyl-CoA + AMP + H+
|
not assigned
|
–
|
| |
MetaCyc:
RXN-21744
|
|
